c. difficile — TargetMol Chemicals

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Search Results for " c. difficile "

Compounds

Cat No.	Product Name	Synonyms	Targets
T1126	Penicillin V Potassium	Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt	Antibacterial , Antibiotic
	Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is a broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.		Antibacterial , Antibiotic
T16748	Ridinilazole	SMT19969	Antibacterial
	Ridinilazole (SMT19969) is a novel narrow-spectrum nonabsorbable antibiotic. Ridinilazole showed potent inhibition of C. difficile (MIC90=0.125 mg/L) and was markedly more active than either metronidazole (MIC90 = 8 mg/L...		Antibacterial
T36585	Isodeoxycholic Acid	isoDCA	Chloride channel , Antibacterial
	Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less...		Chloride channel , Antibacterial
T10243	Ibezapolstat	ACX-362E	Others
	ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections (MIC50: 2 μg/mL for C. difficile).		Others
T76806	Bezlotoxumab
	Bezlotoxumab, a human monoclonal antibody, targets and binds to Clostridium difficile (C. difficile) toxin B, thereby inhibiting its ability to damage intestinal epithelium and cause colitis [1].
T79774	Antibacterial agent 159		Antibiotic
	Compound 6d (Antibacterial agent 159) is an antibiotic effective against impetigo and Clostridium difficile infection (CDI), with no observed recurrence for CDI and minimal impact on the beneficial gut microbiome [1].		Antibiotic
T36075	Cholic Acid anilide
	Cholic acid anilide is a synthetic bile acid and derivative of cholic acid that inhibits the germination of C. difficile strain R20291 spores in vitro (IC50 = 1.8 μM).1 \|1. Sharma, S.K., Yip, C., Esposito, E.X., et al. T...
T78897	Antibacterial agent 156
	Antibacterial Agent 156 (Compound 57), a bactericidal that selectively targets C. difficile cell-wall synthesis, demonstrates potent activity with minimal inhibitory concentrations of 0.5 μg/mL for MIMIC50 (101 strains) ...
T70798	Benastatin B
	Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme).2 Bena...
T61553	ATPase-IN-2
	ATPase-IN-2 is a compound that acts as an inhibitor of ATPase, with an IC50 value of 0.9 μM. It also inhibits the glycohydrolase activity of C. difficile toxin B (TcdB) with an AC50 value of 30.91 μM. ATPase-IN-2 is comm...
T38259	Phenelfamycin E
	Phenelfamycin E is an antibiotic originally isolated from Streptomyces. It is active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus128 μg/ml). Phenelfamycin E (4-64 mg/kg) inc...
T65598	Cefminox sodium
	Cefminox (Sodium) is a new cephamycin antibiotic possessing a D-amino acid moiety derived from D-cysteine at the C-7B side chain. Cefminox is active against a wide range of bacteria, especially Gram-negative and anaerobi...